缪春宝（教授）
Email : chunbao@cczu.edu.cn
教育经历:
2003.9-2006.12中国科学技术大学有机化学专业获博士学位
2000.9-2003.6徐州师范大学 有机化学专业 获硕士学位
1996.9-2000.6徐州师范大学 化学教育专业 获学士学位
工作经历：
2006.12-至今，350vip8888新葡的京集团
2018.10~2019.10，香港科技大学（访问学者）
研究方向:
1. 绿色有机合成
2. 药物合成工艺开发及改进
科研项目:
1. 2022.5-2023.6，酒石酸伐尼克兰的合成工艺开发，常州四药制药有限公司，项目主持人；
2. 2018.7-2021.12，江苏省自然科学金面上项目，基于CDC反应合成α-氨基酸及构建多环螺吲哚的研究，BK20181462，项目主持人；
3. 2019.12-2020.12，MCC和MBQ的合成技术路线和工艺开发，常州四药制药有限公司，项目主持人；
4. 2019.11-2020.03，双缩酮制备醋酸乌立妥环氧物，常州四药制药有限公司，项目主持人；
5. 2009.12-2012.12，江苏省自然科学金，新型1，4－二氢吡啶钙离子通道阻滞剂的设计合成和筛选， BK2009543，项目主持人；
6. 2012.12-2015.12，基于[4+1]或[2+2]或[3+2]反应构建杂环的新方法研究，国家自然科学基金（青年）， 212020111，项目主持人。
发表论文：
1. Hai-Tao Yang,* Su-Qing Zhou, Dan-Mei Chen, Zi-Jun Hu, Xiao-Qi Qiang, Xiao-Qing Song, Sheng Tan, Wei-Hua Jiang, Yong-Qiang Sun, Chun-Bao Miao,* “Copper-Catalyzed Annulation of O‑Acyl Oximes with Cyclic 1,3-Diones for the Synthesis of 7,8-Dihydroindolizin-5(6H)‑ones and Cyclohexanone-Fused Furans”, Org. Lett.2023, 25, 838-842.
2. Chun-Bao Miao,* Xiao-Qi Qiang, Xiaoli Xu, Xiao-Qing Song, Su-Qing Zhou, Xinyu Lyu, Hai-Tao Yang,* “Synthesis of Stable N-H Imines with a Benzo[7,8]indolizine Core and Benzo[7,8]indolizino[1,2-c]quinolines via Copper-Catalyzed Annulation of α,β-Unsaturated O-Acyl Ketoximes with Isoquinolinium N-Ylides”, Org. Lett.2022, 24, 3828-3833.
3. Chun-Bao Miao,* Hong-Rong Guan, YiHan Tang, Kun Wang, Wen-Long Ren, Xinyu Lyu, Changsheng Yao, Hai-Tao Yang,* “Copper-Catalyzed Bisannulations of Malonate-Tethered O‑Acyl Oximes with Pyridine, Pyrazine, Pyridazine, and Quinoline Derivatives for the Construction of Dihydroindolizine-Fused Pyrrolidinones and Analogues”, Org. Lett.2021, 23, 8699-8704.
4. Kun Wang, Hong-Rong Guan, Wen-Long Ren, Hai-Tao Yang,* Chun-Bao Miao,* “Copper-Catalyzed Cascade Annulation of Malonate-Tethered O‑Acyl Oximes with Cyclic 1,3-Dicarbonyl Compounds for the Synthesis of Spiro-Pentacyclic Derivatives”, J. Org. Chem. 2021, 86, 12309-12317.
5. Li-Jin Zhou, Kun Wang, Hong-Rong Guan, An-Qi Zheng, Hai-Tao Yang,* and Chun-Bao Miao,* “Cu(OAc)2‑Promoted Oxidative Cross-Dehydrogenative Coupling Reaction of α‑Acylmethyl Malonates with Indole Derivatives to Access 3‑Functionalized Indoles and Polycyclic Indoles”, J. Org. Chem. 2020, 85, 7925-7938.
6. Chun-Bao Miao,* An-Qi Zheng, Li-Jin Zhou, Xinyu Lyu, and Hai-Tao Yang,* “Copper-Catalyzed Annulation of Oxime Acetates with α‑Amino Acid Ester Derivatives: Synthesis of 3‑Sulfonamido/Imino 4‑Pyrrolin-2-ones”, Org. Lett.2020, 22, 3381-3385.
7. Peng-Fei Mao, Li-Jin Zhou, An-Qi Zheng, Chun-Bao Miao,* Hai-Tao Yang,* “Cu(OAc)2‑Triggered Cascade Reaction of Malonate-Tethered Acyl Oximes with Indoles, Indole-2-alcohols, and Indole-2-carboxamides”, Org. Lett.2019, 21, 5882-5885.
8. Chun-Bao Miao,* Mei-Ling Chen, Xiao-Qiang Sun, Hai-Tao Yang, “DBU-Catalyzed Michael Reaction of Enones with 1,3-Diketones and the Subsequent I2-Mediated Transformation of the Adducts to Polysubstituted Phenols”, Synthesis2019, 51, 2945-2958.
9. Chun-Bao Miao,* Yan-Fang Sun, He Wu, Xiao-Qiang Sun, Hai-Tao Yang, “CuI-Catalyzed Selective 3-Alkylation of Indoles with N-Tosylhydrazones and the I2-Mediated Further Cyclization to Chromeno[2,3-b]Indoles”, Adv. Synth. Catal.2018, 360, 2440-2445.
10. Liu Li, Qiang Jian, Bai Shu-Hua, Sun Hui-Ling, Miao Chun-Bao,* Li Jian,* “Direct Access to Isoindolin-1-one Scaffolds by Copper-Catalyzed Divergent Cyclizations of 2-Formylbenzonitrile and Diaryliodonium Salts”, Adv. Synth. Catal.2017, 359, 1283-1289.
11. Chun-Bao Miao,* Rui Liu, Yan-Fang Sun, Xiao-Qiang Sun, Hai-Tao Yang, “Base-controlled selective construction of polysubstituted dihydrofuran and furan derivatives through an I2-mediated cyclization”, Tetrahedron Lett.2017, 58, 541-545.
12. Ying Shao, Yu-Mei Zeng, Jie-Ying Ji, Xiao-Qiang Sun, Hai-Tao Yang, Chun-Bao Miao,*“The Cs2CO3−Catalyzed Reaction of 2‑Oxindoles with Enones for the Preparation of Indolin-3-Ones and Their Further Transformation”, J. Org. Chem.2016, 81, 12443-12450.
13. Hai-Tao Yang,* Yi-Chen Tan, Jie Ge, He Wu, Jia-Xing Li,* Yang Yang, Xiao-Qiang Sun, Chun-Bao Miao,* “Reaction of C60 with Inactive Secondary Amines and Aldehydes and the Cu(OAc)2‑Promoted Regioselective Intramolecular C−H Functionalization of the Generated Fulleropyrrolidines”, J. Org. Chem.2016, 81, 11201-11209.
14. Chun-Bao Miao,* Yu-Mei Zeng, Tong Shi, Rui Liu, Peng-Fei Wei, Xiao-Qiang Sun, Hai-Tao Yang, “2‑Oxindole Acts as a Synthon of 2‑Aminobenzoyl Anion in the K2CO3‑Catalyzed Reaction with Enones: Preparation of 1,4-Diketones Bearing an Amino Group and Their Further Transformations”, J. Org. Chem.2016, 81, 43-50.
15. Hai-Tao Yang,* Xin-Wei Lu, Meng-Lei Xing, Xiao-Qiang Sun, Chun-Bao Miao,* “Hypervalent Iodine Reagent Mediated Diamination of [60]Fullerene with Sulfamides or Phosphoryl Diamides”, Org. Lett.2014, 16, 5882-5885.
16. Chun-Bao Miao,* Xin-Wei Lu, Ping Wu, Jiaxing Li, Wen-Long Ren, Meng-Lei xing, Xiao-Qiang Sun, Hai-Tao Yang,* “Hypervalent Iodine Reagent-Mediated Reaction of [60]Fullerene with Amines”, J. Org. Chem.2013, 78, 12257-12262.
17. Chun-Bao Miao,*Yan-Hong Wang, Meng-Lei Xing, Xin-Wei Lu, Xiao-Qiang Sun,* and Hai-Tao Yang, “I2-Catalyzed Direct α-Hydroxylation of β-Dicarbonyl Compounds with Atmospheric Oxygen under Photoirradiation” J. Org. Chem.2013, 78, 11584-11589.
18. Hai-Tao Yang,* Wen-Long Ren, Chun-Ping Dong, Yang Yang, Xiao-Qiang Sun, Chun-Bao Miao,* “PhI(OAc)2/I2-mediated [3+2] reaction of [60]fullerene with amides for the preparation of fullerooxazoles”, Tetrahedron Lett.2013, 54, 6799-6803.
19. Chun-Bao Miao,* Chun-Ping Dong, Min Zhang, Wen-Long Ren, Qi Meng, Xiao-Qiang Sun,* Hai-Tao Yang, “Highly Stereoselective, One-Pot Synthesis of Azetidines and 2,4-Dioxo-1,3-diazabicyclo[
20. Chun-Bao Miao,* Min Zhang, Zong-Yong Tian, Hai-Tao Xi, Xiao-Qiang Sun, Hai-Tao Yang,*“Base-Controlled Selective Conversion of Michael Adducts of Malonates with Enones in the Presence of Iodine”, J. Org. Chem.2011, 76, 9809-9816.
