史一安 教授
Email: shiyian@cczu.edu.cn
课题组网站：https://www.x-mol.com/groups/shi_yian
研究方向：
1) 有机合成方法学；2) 不对称合成；3) 生物活性分子的合成与研究
教育背景：
1979-1983，南京大学，化学，学士
1985-1987，加拿大多伦多大学，有机化学，硕士
1987-1992，美国斯坦福大学，有机化学，博士
工作经历：
1992-1995，美国哈佛大学医学院，博士后
1995-2021，美国科罗拉多州立大学化学系，助理教授、副教授、教授
2005-2015，中国科学院化学研究所，研究员，中国科学院分子识别与功能重点实验室主任（2009-2012）
2012-2017，南京大学，化学化工学院，教授
2017-，350vip8888新葡的京集团，350vip8888新葡的京集团，教授，自然与合成有机化学研究院院长
学术荣誉：
l The Camille and Henry Dreyfus New Faculty Award (1995)
l Beckman Young Investigator Award (1997)
l National Science Foundation Career Award (1999)
l Alfred P. Sloan Research Fellowship (1999)
l Camille Dreyfus Teacher-Scholar Award (1999)
l DuPont Young Faculty Award (1999)
l Eli Lilly Grantee Award (1999)
l GlaxoWellcome Inc. Chemistry Scholar Award (2000)
l Researcher of the Year Award, Colorado State University Research Foundation (2000)
l Lectureship Award, The Society of Synthetic Organic Chemistry, Japan (2001)
l Monfort Professorship Award, Colorado State University (2002)
l American Chemical Society Arthur C. Cope Scholar Award (2004)
l Japan Society for the Promotion of Science Fellowship (2009)
l Eun Lee Lectureship Award, Seoul National University, South Korea (2013)
l Fellow of Royal Society of Chemistry (2017)
l International Organic Chemistry Foundation (IOCF), Yoshida Lectureship Award (2017)
部分代表性论文：
l Jianjun Wang, Daguo Hu, Xiaofeng Sun, Huiying Hong, & Yian Shi. “Pd-Catalyzed Aryl C-H Amination with Diaziridinone”, Org. Lett. 2023, 25, 2006−2011.
l Junhua Li & Yian Shi. “Progress on Transition Metal Catalyzed Asymmetric Hydroesterification, Hydrocarboxylation, and Hydroamidation Reactions of Olefins”, Chem. Soc. Rev. 2022, 51, 6757-6773.
l Wenlong Ren, Mingzhou Wang, Jianqiong Guo, Jintao Zhou, Jianxiao Chu, Yuan Shi, & Yian Shi. “Pd-Catalyzed Regioselective Branched Hydrocarboxylation of Terminal Olefins with Formic Acid”, Org. Lett. 2022, 24, 886-891.
l Sudarshan Debnath, Mei Lu, Lingli Liang, & Yian Shi. “A Tandem Nucleophilic Aminopalladation and Carbene Insertion Sequence for Indole Fused Polycles”, Org. Lett. 2021, 23, 7188-7122.
l Jing Li, Jinhua Chen, Luying Wang, & Yian Shi. “Palladium-Catalyzed Sequential C-H Activation/Amination with Diaziridinone: An Approach to Indoles”, Org. Lett. 2021, 23, 3646-3651.
l Wenlong Ren, Fei Sun, Jianxiao Chu, & Yian Shi. “A Pd-Catalyzed Site-Controlled Isomerization of Terminal Olefins”, Org. Lett. 2020, 22, 1868-1873.
l Wenlong Ren, Jianxiao Chu, Fei Sun, & Yian Shi. “Pd-Catalyzed Highly Chemo- and Regioselective Hydrocarboxylation of Terminal Alkyl Olefins with Formic Acid”, Org. Lett. 2019, 21, 5967-5970.
l Qipu Dai, Baoguo Zhao, Yihui Yang, & Yian Shi. “Pd-Catalyzed Oxidative Heck Reaction of Grignard Reagents with Diaziridinone as Oxidant”, Org. Lett. 2019, 21, 5157-5161.
l Jie Dai, Wenlong Ren, Jingfu Li, & Yian Shi. “An Effective Approach to Aryl-Substituted Propanoic Acids via Pd-Catalyzed Hydrocarboxylation of Stilbenes”, Org. Chem. Front. 2018, 5, 561-565.
l Jingfu Li, Wenlong Ren, Jie Dai, & Yian Shi. “Palladium-Catalyzed Regio- and Enantioselective Hydroesterification of Aryl Olefins with CO Gas”, Org. Chem. Front. 2018, 5, 75-79.
l Wenlong Ren, Wengju Chang, Jie Dai, Yuan Shi, Jingfu Li, & Yian Shi. “An Effective Pd-Catalyzed Regioselective Hydroformylation of Olefins with Formic Acid”, J. Am. Chem. Soc. 2016, 138, 14864-14867.
l Ying Xie, Hongjie Pan, Mao Liu, Xiao Xiao, & Yian Shi. “Progress in Asymmetric Biomimetic Transamination of Carbonyl Compounds”, Chem. Soc. Rev. 2015, 44, 1740-1748.
l Yingguang Zhu, Richard G. Cornwall, Haifeng Du, Baoguo Zhao, & Yian Shi. “Catalytic Diamination of Olefins via N-N Bond Activation”, Acc. Chem. Res. 2014, 47, 3665-3678.
l Huaiji Zheng, Yingguang Zhu, & Yian Shi. “Palladium (0)-Catalyzed Heck Reaction/C-H Activation/Amination Sequence with Diaziridinone: A Facile Approach to Indolines”, Angew. Chem. Int. Ed. 2014, 53, 11280-11284.
l Yingguang Zhu, Qian Wang, Richard G. Cornwall, & Yian Shi. “Oranocatalytic Asymmetric Epoxidation and Aziridination of Olefins and their Synthetic Applications”, Chem. Rev. 2014, 114, 8199-8256.
l Deshun Huang, Xiaoqin Liu, Lijun Li, Yudong Cai, Weigang Liu, & Yian Shi. “Enantioselective Bromoaminocyclization of Allyl N-Tosylcarbamates Catalyzed by a Chiral Phosphine-Sc(OTf)3 Complex”, J. Am. Chem. Soc. 2013, 135, 8101-8104.
l Thomas A. Ramirez, Baoguo Zhao, & Yian Shi. “Recent Advances in Transition Metal-Catalyzed sp3 C-H Amination Adjacent to Double Bonds and Carbonyl Groups”, Chem. Soc. Rev. 2012, 41, 931-942.
l Baoguo Zhao, Xingao Peng, Yingguang Zhu, Thomas A. Ramirez, Richard G. Cornwall, & Yian Shi. “Cu(I)-Catalyzed Diamination of Conjugated Dienes. Complementary Regioselectivity from Two Distinct Mechanistic Pathways Involving Cu(II) and Cu(III) Species”, J. Am. Chem. Soc. 2011, 133, 20890-20900.
l Xiao Xiao, Ying Xie, Cunxiang Su, Mao Liu, & Yian Shi. “Organocatalytic Asymmetric Biomimetic Transamination: From a-Keto Esters to Optically Active a-Amino Acid Derivatives”, J. Am. Chem. Soc. 2011, 133, 12914-12917.
l Baoguo Zhao, Xingao Peng, Sunliang Cui, & Yian Shi. “Cu(I)-Catalyzed Regioselective Diamination of Conjugated Dienes via Dual Mechanistic Pathways”, J. Am. Chem. Soc. 2010, 132, 11009-11011.
l Baoguo Zhao, Haifeng Du, Sunliang Cui, & Yian Shi. “Synthetic and Mechanistic Studies on Pd(0)-Catalyzed Diamination of Conjugated Dienes”, J. Am. Chem. Soc. 2010, 132, 3523-3532.
l Bin Wang, Haifeng Du, & Yian Shi. “A Palladium-Catalyzed Dehydrogenative Diamination of Terminal Olefins”, Angew. Chem. Int. Ed. 2008, 47, 8224-8227.
l O. Andrea Wong & Yian Shi. “Organocatalytic Oxidation. Asymmetric Epoxidation of Olefins Catalyzed by Chiral Ketones and Iminium Salts”, Chem. Rev. 2008, 108, 3958-3987.
l Haifeng Du, Baoguo Zhao, & Yian Shi. “Catalytic Asymmetric Allylic and Homoallylic Diamination of Terminal Olefins via Formal C-H Activation”, J. Am. Chem. Soc. 2008, 130, 8590-8591.
l Baoguo Zhao, Haifeng Du, & Yian Shi. “A Cu(I)-Catalyzed C-H a-Amination of Esters. Direct Synthesis of Hydantoins”, J. Am. Chem. Soc. 2008, 130, 7220-7221.
l Haifeng Du, Weicheng Yuan, Baoguo Zhao, & Yian Shi. “Catalytic Asymmetric Diamination of Conjugated Dienes and Triene”, J. Am. Chem. Soc. 2007, 129, 11688-11689.
l Haifeng Du, Weicheng Yuan, Baoguo Zhao, & Yian Shi. “A Pd(0)-Catalyzed Diamination of Terminal Olefins at Allylic and Homoallylic Carbons via Formal C-H Activation under Solvent-Free Conditions”, J. Am. Chem. Soc. 2007, 129, 7496-7497.
l Haifeng Du, Baoguo Zhao, & Yian Shi. “A Facile Pd(0)-Catalyzed Regio- and Stereoselective Diamination of Conjugated Dienes and Trienes”, J. Am. Chem. Soc. 2007, 129, 762-763.
l Yu-Mei Shen, Mei-Xin Zhao, Jiaxi Xu, & Yian Shi. “An Amine-Promoted Aziridination of Chalcones”, Angew. Chem. Int. Ed. 2006, 45, 8005-8008.
l Christopher P. Burke & Yian Shi. “Regio- and Enantioselective Epoxidation of Dienes by a Chiral Dioxirane: Synthesis of Optically Active Vinyl cis-Epoxides”, Angew. Chem. Int. Ed. 2006, 45, 4475-4478.
l Yu-Mei Shen, Bin Wang, & Yian Shi. “Enantioselective Synthesis of 2-Aryl Cyclopentanones by Asymmetric Epoxidation and Epoxide Rearrangement”, Angew. Chem. Int. Ed. 2006, 45, 1429-1432.
l Yian Shi. Organocatalytic Asymmetric Epoxidation of Olefins by Chiral Ketones, Acc. Chem. Res. 2004, 37, 488-496.
l Matthew Hickey, David Goeddel, Zackary Crane, & Yian Shi. Highly Enantioselective Epoxidation of Styrenes: Implication of an Electronic Effect on the Competition between Spiro and Planar Transition States, Proc. Natl. Acad. Sci. USA 2004, 101, 5794-5798.
l Jiang Long, Yi Yuan, & Yian Shi. Asymmetric Simmons-Smith Cyclopropanation of Unfunctionalized Olefins, J. Am. Chem. Soc. 2003, 125, 13632-13633.
l Xin-Yan Wu, Xuegong She, & Yian Shi. Highly Enantioselective Epoxidation of a,b-Unsaturated Esters by Chiral Dioxirane, J. Am. Chem. Soc. 2002, 124, 8792-8793.
l Hongqi Tian, Xuegong She, Lianhe Shu, Hongwu Yu, & Yian Shi. Highly Enantioselective Epoxidation of cis-Olefins by Chiral Dioxirane, J. Am. Chem. Soc. 2000, 122, 11551-11552.
l Xiaoming Feng, Lianhe Shu, & Yian Shi. Complete Conversion of Racemic Enol Ester Epoxides into Optically Active a-Acyloxy Ketones, J. Am. Chem. Soc. 1999, 121, 11002-11003.
l Michael Frohn, Xiaoming Zhou, Jian-Rong Zhang, Yong Tang, & Yian Shi. Kinetic Resolution of Racemic Cyclic Olefins via Chiral Dioxirane, J. Am. Chem. Soc. 1999, 121, 7718-7719.
l Yuanming Zhu, Karl J. Manske, & Yian Shi. Dual Mechanisms of Acid-Catalyzed Rearrangement of Enol Ester Epoxides: Enantioselective Formation of aa-Acyloxy Ketones, J. Am. Chem. Soc. 1999, 121, 4080-4081.
l Zhi-Xian Wang, Yong Tu, Michael Frohn, Jian-Rong Zhang, & Yian Shi. An Efficient Catalytic Asymmetric Epoxidation Method, J. Am. Chem. Soc. 1997, 119, 11224-11235.
l Yong Tu, Zhi-Xian Wang, & Yian Shi. An Efficient Asymmetric Epoxidation Method for trans-Olefins Mediated by a Fructose-Derived Ketone, J. Am. Chem. Soc. 1996, 118, 9806-9807.
